2021 AOSSM-AANA Combined Annual Meeting Recordings-Development of Immune-Directed Cartilage Bioprinting Platform

Video Transcription

Video Summary

The video transcript is a presentation by Brian Cole, who is part of a team at the Wake Forest Institute of Regenerative Medicine. The team is proposing a novel immune-directed cartilage bioprinting platform for the treatment of chondral defects and post-traumatic osteoarthritis (PTOA). They aim to use mononuclear cells and mesenchymal stem cells (MSCs) to direct end cell differentiation and regenerate damaged cartilage. The team has conducted in vitro and in vivo experiments to validate their approach and has shown promising results in chemically-induced osteoarthritis models. They also plan to use bioprinting technology to create customized scaffolds for the regeneration of focal chondral defects. The team is seeking funding to support their research and believes that their approach could revolutionize tissue engineering and lead to improved strategies for musculoskeletal restoration.<br /><br />Credits: This video presentation is given by Brian Cole from the Wake Forest Institute of Regenerative Medicine, with acknowledgements to the team collaborators, including Dr. Gary Paling, Dr. Anthony Atala, Dr. Gustavo Moviglia, Dr. Carlos Cangla, Johanna, and Gary.

Asset Caption

Brian Waterman, MD

Keywords

immune-directed cartilage bioprinting

chondral defects

post-traumatic osteoarthritis

mesenchymal stem cells

customized scaffolds

tissue engineering