2018 Orthobiologics Surgical Skills Online-6 - Amniotic by Kevin D Plancher, MD, MPH

Video Transcription

Video Summary

In this video, the speaker discusses the advantages of using amniotic cells for tissue regeneration. These cells are highly plastic and can differentiate into various lineages. They also contain growth factors that are 10 times more potent than those found in bone marrow aspirates. Furthermore, amniotic cells have low immunogenicity and possess anti-inflammatory properties. The speaker presents comparisons between amniotic stem cells and bone marrow aspirates in terms of healing potential and proliferative capacity. They also mention the use of amniotic stem cells in treating tendinopathy and the positive results observed in animal studies. The video highlights the need for further research and regulation in the field of amniotic stem cell therapy, as there are many different products available with varying efficacy. The speaker introduces two types of amniotic stem cell products – cryopreserved cells and dehydrated intact cells, and discusses their usage and potential benefits. However, the speaker admits that more research is needed to fully understand the mechanism of action and the optimal concentration for these therapies. The cost of the treatment is mentioned, as well as the availability of a J code for reimbursement. The video concludes with a discussion on the different outcomes observed between cryopreserved and dehydrated intact cells.

Keywords

amniotic cells

tissue regeneration

differentiation

growth factors

immunogenicity