CC2021: A Systematic Review of Basic Science and Animal Studies on the Use of Doxycycline to Reduce the Risk of Posttraumatic Osteoarthritis After Anterior Cruciate Ligament Rupture/Transection (July 2021)

Information

LEARNING OBJECTIVES
Upon completion of this educational activity, participants should be able to:

Describe the incidence of posttraumatic osteoarthritis after anterior cruciate ligament injury in human patients and the risk of future total knee arthroplasty in these patients.
Explain the current basic science evidence of doxycycline for the prevention of posttraumatic osteoarthritis after anterior cruciate ligament rupture/transection.
Detail the molecular changes that occur after doxycycline treatment with regard to the articular cartilage.

DISCLOSURES
AUTHORS
Matthew J. Kraeutler, MD
Nothing to disclose

Please note, all author disclosures related to writing the AJSM article are included in the article PDF. Author disclosures related to this educational activity are located above.

EDITORS
Bruce Reider, MD
Merck - Stockholder
Elsevier - Royalties
Johnson & Johnson - Stockholder

Timothy Foster, MD
Nothing to disclose

Bert R. Mandelbaum, MD
Arthrex - Royalties
Arthrex, DePuy - A Johnson & Johnson Company, Exactech - Paid consultant

PLANNERS
Donna Tilton
Nothing to disclose

ORIGINAL RELEASE DATE: July 1, 2021
TERMINATION DATE: June 30, 2024

ACCREDITATION STATEMENT
The American Orthopaedic Society for Sports Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

AMA CREDIT DESIGNATION STATEMENT
The American Orthopaedic Society for Sports Medicine designates this Journal-based CME activity for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

CLAIMING CREDIT
In order to obtain AMA PRA Category 1 Credit™ participants must receive a score of 80% or higher on the post test. Participants have up to five attempts to pass. The evaluation also must be completed. Please note that this is an online-only activity. Participants must complete the post test and evaluation online. No hard copy submissions will be accepted.

DISCLAIMER
The material presented in this continuing medical education program is being made available by the American Orthopaedic Society for Sports Medicine for educational purposes only. This material is not intended to represent the only, nor necessarily the best, methods or procedures appropriate for the medical situation discussed, but rather is intended to present an approach, view, statement, or opinion of the authors, which may be helpful, or of interest, to other practitioners. AOSSM is not responsible for expenses incurred by an author. Costs incurred by the registrant are the responsibility of the registrant.

Summary


Availability:	Retired


Cost:	$15.00


Credit Offered:	No Credit Offered