CC2023: Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials (March 2023)

Information

LEARNING OBJECTIVES
Upon completion of this educational activity, participants should be able to:

Discuss the clinical efficacy and safety of intra-articular injection of autologous adipose-derived mesenchymal stem cells (ASCs) and adipose-derived stromal vascular fractions for patients with knee osteoarthritis
Determine the level of evidence for the efficacy for cartilage regeneration in knee osteoarthritis
Determine the level of evidence for the efficacy between ASC and ADSVF treatments

DISCLOSURES
AUTHORS
Jun-Ho Kim, MD, PhD
Nothing to disclose

Please note, all author disclosures related to writing the AJSM article are included in the article PDF. Author disclosures related to this educational activity are located above.

EDITORS
Bruce Reider, MD
Merck - Stockholder
Elsevier - Royalties
Johnson & Johnson - Stockholder

Timothy Foster, MD
Nothing to disclose

Bert R. Mandelbaum, MD
Arthrex - Royalties
Arthrex, DePuy - A Johnson & Johnson Company, Exactech - Paid consultant

PLANNERS
Donna Tilton
Nothing to disclose

ORIGINAL RELEASE DATE: March 1, 2023
TERMINATION DATE: February 28, 2026

ACCREDITATION STATEMENT
The American Orthopaedic Society for Sports Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

AMA CREDIT DESIGNATION STATEMENT
The American Orthopaedic Society for Sports Medicine designates this Journal-based CME activity for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

CLAIMING CREDIT
In order to obtain AMA PRA Category 1 Credit™ participants must receive a score of 80% or higher on the post test. Participants have up to five attempts to pass. The evaluation also must be completed. Please note that this is an online-only activity. Participants must complete the post test and evaluation online. No hard copy submissions will be accepted.

DISCLAIMER
The material presented in this continuing medical education program is being made available by the American Orthopaedic Society for Sports Medicine for educational purposes only. This material is not intended to represent the only, nor necessarily the best, methods or procedures appropriate for the medical situation discussed, but rather is intended to present an approach, view, statement, or opinion of the authors, which may be helpful, or of interest, to other practitioners. AOSSM is not responsible for expenses incurred by an author. Costs incurred by the registrant are the responsibility of the registrant.

Summary


Availability:	On-Demand
	Expires on 02/28/2026


Cost:	Member: $15.00 Resident/Fellow Member: $15.00 Affiliate Member: $15.00 Non-Member: $25.00


Credit Offered:	1 CME Credit