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OCD Fixation: 8. Is There a Role for Biologics in ...
OCD Fixation: 8. Is There a Role for Biologics in OCD or Meniscus Treatment
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Video Transcription
Video Summary
In the video, Melissa Cristino from Boston Children's Hospital discusses the role of biologics in the treatment of meniscus and osteochondritis dissecans (OCD) injuries. She mentions the AOS biologic dashboard as a helpful resource for interpreting the literature on orthobiologics. For meniscal injuries, a study showed that intra-articular PRP injection in adolescent patients resulted in improved outcomes with less pain. However, there were limitations to the study, including a small sample size and lack of a control group. Mixed evidence exists for the use of PRP in meniscal repair, with some studies showing improved healing and others showing no effect. BMAC (bone marrow aspirate concentrate) has shown potential benefits in treating OCD and chondral lesions, but the studies lack scientific rigor. Cartilage restoration procedures, such as OCA and ACI, are considered for unsalvageable OCD lesions. Studies have shown good graft survivorship and functional outcomes following these procedures. Safe interventions include PRP and autologous blood, but more comparative studies are needed in pediatric patients to determine their effectiveness.
Keywords
biologics
meniscus injuries
osteochondritis dissecans
PRP injection
cartilage restoration
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