Management of the Athlete’s Knee Event Recording-10. You Want Fries with That? Applications For BMAC, and the Best of the Rest: Lipogens, Amniotic, Umbilical, Placental, Etc.

10. You Want Fries with That? Applications For BMAC, and the Best of the Rest: Lipogens, Amniotic, Umbilical, Placental, Etc.

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Video Summary

In this video, Dr. Jason Dragoo discusses the use of adipose tissue and bone marrow concentrate in orthopedic surgery. Adipose tissue, or fat tissue, is chosen as a biologic due to its high concentration of mesenchymal stem cells (MSCs) compared to other sources like bone marrow. These cells have been shown to relieve pain and have anti-inflammatory properties. Adipose tissue has been used for the treatment of articular cartilage defects and osteoarthritis. The harvesting of adipose tissue involves techniques such as tumescent liposuction or arthroscopic harvesting. The fat can be processed using methods like ball bearing-based systems or syringe emulsification to make it more bioactive. Studies have shown that these techniques decrease pain and improve function. <br /><br />Bone marrow aspirate is another source of MSCs. Technique is critical in harvesting bone marrow and concentration has been shown to be beneficial. It is commonly used for improving rotator cuff repair and treating tendinopathy. However, it is important to note that the use of birth products like amniotic fluid and cord blood in orthopedic surgery is currently illegal, except in FDA IND studies.<br /><br />Overall, adipose tissue technologies have shown to be beneficial for reducing pain and inflammation in osteoarthritis, while bone marrow concentrate has been effective in improving rotator cuff healing and treating tendinopathy.

Asset Caption

Jason L. Dragoo, MD

Keywords

adipose tissue

bone marrow concentrate

orthopedic surgery

mesenchymal stem cells

treatment