IC304-2021: Hype, Promise, and Reality: Orthopedic Use of Biologics in 2021-Hype, Promise, and Reality: Orthopedic Use of Biologics in 2021' (1/4)

Video Transcription

Video Summary

In this video, the speaker discusses various techniques and advancements in regenerative medicine, specifically focusing on cartilage regeneration. The speaker begins by mentioning the role of the FDA in regulating the use of regenerative medicine products and removing misleading and misused ones from the market. They then explain the renaming of stem cell therapy to cellular therapy, highlighting that as stem cells age, they lose their ability to generate all types of cells in the body.<br /><br />The speaker goes on to discuss the therapeutic effects of cellular medicine, including pain relief and anti-inflammatory properties. They provide an overview of the techniques used to harvest and process bone marrow and adipose-derived cells for cartilage regeneration, emphasizing the importance of proper technique. They also mention ongoing trials and the need for more research in these areas.<br /><br />The speaker explores the potential of using juvenile chondrocytes and allogenic umbilical cord cells for cartilage regeneration. They caution against the use of processed allogenic products and highlight the importance of understanding biology and safety mechanisms behind such treatments.<br /><br />Lastly, the speaker discusses techniques for remodeling subchondral bone, including the use of drills and injections. They emphasize the significance of addressing underlying abnormal bone conditions for successful cartilage regeneration. The video concludes with the speaker mentioning ongoing studies and the need for further research in the field.

Asset Caption

Jason Dragoo, MD

Keywords

regenerative medicine

cartilage regeneration

cellular therapy

bone marrow

adipose-derived cells

subchondral bone remodeling