CC2022: Current Trends in Orthobiologics: An 11-Year Review of the Orthopaedic Literature (September 2022)-Current Trends in Orthobiologics: An 11-Year Review of the Orthopaedic Literature (September 2022)

Current Trends in Orthobiologics: An 11-Year Review of the Orthopaedic Literature (September 2022)

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This study conducted a systematic review of the orthopedic literature to evaluate trends in the use of orthobiologics and assess the need for standardized reporting standards. The study focused on four commonly used orthobiologics: platelet-rich plasma (PRP), bone marrow aspirate (BMA), adipose-derived cells (ADCs), and amniotic cells. <br /><br />The study found that the use of orthobiologics has been growing steadily over the past 11 years, reflected by the increasing publication volume in major orthopedic journals. PRP had the highest total publication volume, with the American Journal of Sports Medicine (AJSM) publishing the most articles on PRP. <br /><br />However, the study also revealed that current reporting on orthobiologic formulations is largely heterogeneous. Only a small proportion of the included articles utilized minimum reporting standards. The authors proposed a universally adopted reporting protocol that includes essential parameters such as donor information, formulation characteristics, disease of interest, delivery protocol, postoperative protocol, and outcomes. They suggested that journals and professional societies should encourage the widespread adoption of minimum reporting standards to improve the transparency and reproducibility of orthobiologic research.<br /><br />The study also identified variation in the utilization of different orthobiologics for various musculoskeletal conditions. PRP and BMA accounted for the majority of clinical research articles included in the study. <br /><br />In conclusion, while the use of orthobiologics in orthopedic surgery is growing, there is a need for standardized reporting standards and higher-quality studies. The proposed reporting protocol aims to address this issue and improve the transparency and reproducibility of orthobiologic research.

Keywords

orthopedic literature

orthobiologics

standardized reporting standards

platelet-rich plasma

bone marrow aspirate

adipose-derived cells

amniotic cells

publication volume

minimum reporting standards

transparency