AOSSM 2023 Annual Meeting Recordings no CME-Serum Biochemical Biomarker Profiles Linked to Poor Knee Joint Health Are Not Associated with OA-Related Symptoms at 12 Months Post-ACLR

Serum Biochemical Biomarker Profiles Linked to Poor Knee Joint Health Are Not Associated with OA-Related Symptoms at 12 Months Post-ACLR

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Video Summary

In this video, an assistant professor at the University of Georgia discusses a study on identifying individuals at risk for developing post-traumatic osteoarthritis (PTOA) after ACL injury. The study focused on changes in serum biomarkers related to inflammation and cartilage breakdown. The researcher explains that these biomarkers have been found to be elevated in previous studies. The participants in the study underwent ACL reconstruction surgery and filled out a survey on knee function at 12 months post-surgery. The study found two profiles based on changes in biomarkers, but there were no significant associations between these profiles and clinically relevant PTOA symptoms. However, the biomarker changes may still be useful for identifying those at risk for poor tibiofemoral cartilage health. The researcher thanks the UNC Department of Orthopedics for their support.

Asset Caption

Caroline Lisee, PhD, ATC

Keywords

post-traumatic osteoarthritis

ACL injury

serum biomarkers

knee function

tibiofemoral cartilage health