AOSSM 2022 Annual Meeting Recordings - no CME-Sex Mismatch Between Donor and Recipient is Associated with Decreased Graft Survivorship at 5-years After Osteochondral Allograft Transplantation

Sex Mismatch Between Donor and Recipient is Associated with Decreased Graft Survivorship at 5-years After Osteochondral Allograft Transplantation

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Video Summary

In the video, the speaker discusses the association of sex mismatch between donor and recipient with graft survivorship at five years after osteochondral allograft (OCA) transplantation. They explain that OCA transplantation is an effective strategy for treating large cartilage defects, but there is still variation in graft survival rates. Factors like patient characteristics and graft viability have been studied as predictors for OCA failure. However, the speaker focuses on the potential role of sex matching between the donor and recipient. They conducted a study on patients who underwent OCA transplantation and found that sex mismatched OCAs had a significantly higher likelihood of failure compared to sex matched OCAs. Male-to-female mismatched allografts had the worst survival rate. The speaker suggests that efforts should be made to avoid donor-recipient sex mismatch to improve the long-term success of OCA transplantation.

Asset Caption

Chilan Leite, MD

Keywords

sex mismatch

graft survivorship

osteochondral allograft transplantation

graft failure

donor-recipient sex matching