AOSSM 2022 Annual Meeting Recordings - no CME-How to Review a Large Database Study

Video Transcription

Video Summary

In this video, the speaker discusses large database studies, their strengths, and limitations. They emphasize the importance of accurate classification and counting in these studies, as well as the influence of numerators and denominators on the findings. The speaker also talks about statistical considerations, such as confidence intervals, multiple hypothesis testing, and adjusting p-values. They explain the difference between prospective and retrospective roles of chance in data analysis. The critical reviewer is advised to assess the numerators and denominators chosen by the authors, evaluate the statistics used, and consider the clinical relevance of the findings. The speaker also addresses audience questions about Bonferroni correction, clinical significance, and minimal clinically important difference. Overall, the video provides insights into reviewing and interpreting large database studies.

Asset Caption

James L. Carey, MD, MPH

Keywords

large database studies

numerators

denominators

statistics

clinical relevance

interpreting