2022 AOSSM Annual Meeting Recordings with CME-Sex Mismatch Between Donor and Recipient is Associated with Decreased Graft Survivorship at 5-years After Osteochondral Allograft Transplantation

Sex Mismatch Between Donor and Recipient is Associated with Decreased Graft Survivorship at 5-years After Osteochondral Allograft Transplantation

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Video Summary

In this video, the speaker discusses the association of sex mismatch between donor and recipient with graft survivorship at five years after osteochondral autograft (OCA) transplantation. The speaker mentions that OCA transplantation is an effective strategy for treating large cartilage defects but that graft survival rates vary. The study aims to explore the potential effect of donor-recipient sex mismatch on OCA transplantation in the knee. The findings show that sex-mismatched OCAs have a higher likelihood of failure compared to sex-matched OCAs, with male-donor-to-female-recipient combinations having the worst survivorship. The speaker suggests that efforts to avoid donor-recipient sex mismatch may improve the long-term success of OCA transplantation.

Asset Caption

Chilan Leite, MD

Keywords

sex mismatch

graft survivorship

osteochondral autograft transplantation

cartilage defects

donor-recipient sex mismatch