2022 AOSSM Annual Meeting Recordings with CME-Senolytics and Senescent Cells in Cartilage Repair

Senolytics and Senescent Cells in Cartilage Repair

Video Transcription

Video Summary

In this video, the speaker discusses the role of cellular senescence in osteoarthritis (OA) and the potential use of senolytic drugs to delay cartilage degeneration. The speaker presents findings from animal models and clinical trials, showing that senolytic drugs can reduce senescent cells and inflammatory mediators in the blood of OA patients. They also discuss ongoing studies and collaborations with other institutions. Overall, the speaker emphasizes the importance of evidence-based treatments and collaboration between scientists and orthopedic surgeons in developing new treatments for OA. The speaker expresses gratitude to their team and collaborators.

Asset Caption

Johnny Huard, PhD

Keywords

cellular senescence

osteoarthritis

senolytic drugs

cartilage degeneration

inflammatory mediators