2022 AOSSM Annual Meeting Recordings with CME-Long-term Outcomes of an All-Arthroscopic Matrix-Assisted Autologous Chondrocyte Transplantation Technique

Long-term Outcomes of an All-Arthroscopic Matrix-Assisted Autologous Chondrocyte Transplantation Technique

Video Transcription

Video Summary

In this video presentation, Antonio discusses a study on matrix-assisted autologous chondrocyte transplantation (third-generation ACI) as a long-term alternative for treating cardiac lesions in arthroscopic surgeries. The study included 36 patients with grade III or IV cartilage lesions who underwent the transplantation procedure. Follow-up was conducted over a 10-year period using magnetic resonance imaging and patient-reported outcome measures. Results showed that the T2 mapping values between healthy cartilage and repair tissue decreased over time. MOACART scores remained stable, and arthroscopic second look assessments indicated nearly normal cartilage. Patients reported improved clinical outcomes after 10 years, with no major decline. Limitations included a small sample size and lack of a control group. The study suggests that matrix-assisted autologous chondrocyte transplantation could be a lasting option for focal chondral lesions in the knee.

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Antonio Madrazo-Ibarra, MD

Keywords

matrix-assisted autologous chondrocyte transplantation

third-generation ACI

cardiac lesions

arthroscopic surgeries

cartilage lesions