2022 AOSSM Annual Meeting Recordings with CME-Leukocyte-Poor Platelet Rich Plasma versus Leukocyte-Poor Platelet Rich Plasma Plus Hyaluronic Acid for the Treatment of Symptomatic Knee Osteoarthritis: A Prospective, Randomized Control Trial with 2 Year Follow Up

Leukocyte-Poor Platelet Rich Plasma versus Leukocyte-Poor Platelet Rich Plasma Plus Hyaluronic Acid for the Treatment of Symptomatic Knee Osteoarthritis: A Prospective, Randomized Control Trial with 2 Year Follow Up

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Video Transcription

Video Summary

In this video, the speaker discusses the results of a randomized controlled trial prospective study on the use of hyaluronic acid (HA) with platelet-rich plasma (PRP) in the treatment of osteoarthritis. The study was not industry-sponsored and was funded by a grant from the state of Florida. The speaker explains the importance of the translational medicine process and how both HA and PRP have been through this process before. The study included individuals diagnosed with osteoarthritis and used different outcome measures to assess improvements. The results showed significant improvements in Womack, KOOS, and IKDC scores at one month, which plateaued at three months and sustained for 24 months. The study concluded that both PRP and the addition of HA were effective for at least 24 months, with no superiority of PRP plus HA over PRP alone. The speaker acknowledges their co-authors and research team for their contributions to the study.

Asset Caption

Adam Anz, MD

Keywords

randomized controlled trial

prospective study

hyaluronic acid

platelet-rich plasma

osteoarthritis