2022 AOSSM Annual Meeting Recordings with CME-Effect of Bone Marrow Aspirate Concentrate on Osteochondral Allograft Transplantation Incorporation: A Prospective, Randomized, Single Blind Investigation

Effect of Bone Marrow Aspirate Concentrate on Osteochondral Allograft Transplantation Incorporation: A Prospective, Randomized, Single Blind Investigation

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Video Transcription

Video Summary

In this video, the speaker discusses the use of bone marrow aspirate concentrate as an adjunct treatment for osteochondroallograft transplantation in knee cartilage defects. They review previous studies and explain their own study, which aimed to investigate the effect of graft pretreatment with bone marrow aspirate concentrate on integration and patient-reported outcomes. They recruited 36 patients, randomized to receive either bone marrow aspirate concentrate or a sham treatment. CT scans and patient-reported outcomes were evaluated at six months and one year. The results showed no significant difference in osseointegration or patient-reported outcomes, but a trend towards smaller cystic changes at the graft-host interface with bone marrow aspirate concentrate. Further research is needed to confirm these findings. No credits are mentioned in the video.

Asset Caption

Nicholas Trasolini, MD

Keywords

bone marrow aspirate concentrate

osteochondroallograft transplantation

knee cartilage defects

graft pretreatment

patient-reported outcomes